Hepaticstellatecells相关论文
Ethyl Acetate Fraction of Dicliptera chinensis (L.) Juss.Ameliorates Liver Fibrosis by Inducing Auto
Objective:To investigate the molecular mechanism underlying the anti-hepatic fibrosis activity of ethyl acetate fraction......
Pantoprazole ameliorates liver fibrosis and suppresses hepatic stellate cell activation in bile duct
Liver fibrosis is one of the most severe pathologic consequences of chronic liver diseases,and effective therapeutic str......
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Wnt5a participates in hepatic stellate cell activation observed by gene expression profile and funct
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MSC-conditioned medium alleviates acute liver injury and chronic liver fibrosis via acting on hepato
BACKGROUND: Liver is the most important metabolic organ for a majority of animals.Therefore, Liver failure,including acu......
Background: Both acute liver injury and chronic liver fibrosis can lead to a potentially life-threatening condition, liv......
Aim: To investigate the distribution and function of α1-adenoreceptor subtypes (α1-AR) in rat hepatic stellate cells (......
Thymoquinone down-regulation lipopolysaccharide-induced TLR4 signaling via suppressing nuclear facto
OBJECTIVE Thymoquinone (TQ) is the major active compound derived from the medicinal Nigella sativa.It has been shown to ......
P2X7 receptor (P2X7r) is important in inflammation and fibrosis.The aim of the present study was to investigate the effe......
Sphingosine Kinase/Sphingosine 1-Phosphate (S1P)/S1P Receptor Axis is Involved in Liver Fibrosis-Ass
Background/Aims:Sphingosine kinase (SphK)/sphingosine 1-phosphate (S1P)/S 1P.receptor (S1PR) axis is involved in multipl......
Role of LncRNA-activated by transforming growth factor beta in the progression of hepatitis C virus-
Long non-coding RNA (LncRNA)-activated by transforming growth factor-beta (LncRNA-ATB) is a key regulator of transformin......
Inhibition of Notch signaling pathway prevented cholestatic liver fibrosis through decrease the diff
Although hepatic progenitor cells(HPCs)are known to contribute to cholestatic liver fibrosis(CLF),how Notch signaling mo......
Adiponectin-derived active peptide ADP355 exerts anti-inflammatory and anti-fibrotic activities in t
Background & Aims: Adiponectin is an adipocyte-derived circulating protein with beneficial effects on liver injury.Mice ......
Aim: Liver Kinase B1 (LKB1) proteins serve as a master regulator of metabolismthat inhibits anabolic processes and stimu......
MiR-1273g-3p affects activation and apoptosis of hepatic stellate cells by directly targeting PTEN i
Aberrant microRNAs (miRNAs) expression plays a privotal role in the development of liver fibrosis.However,the functional......
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Activation of hepatic stellate cells (HSCs) by transforming growth factor-β1 (TGF-β1) initiates HBV-associated fibroge......
Use of Human Umbilical Cord Mesenchymal Stem Cells for the Treatment of Carbon tetrachloride-induced
Mesenchymal stem cells (MSCs), a population of multipotent progenitors capable of differentiating into adipogenic, osteo......
Potent effects of dioscin against thioacetamide-induced liver fibrosis through attenuating oxidative
The protective effects and mechanisms of dioscin against liver fibrosis were investigated.The results showed that diosci......
Ligustrazine stimulates apoptosis of rat hepatic stellate cells through regulation of Bcl-2/Bax prot
Objective:Accumulating experimental and clinical studies provide clear evidence for reversibility of hepatic fibrosis (H......
Ligustrazine-induced apoptosis is involved in its regulation of expression of Bcl-2 and Bax by caspa
Aims: Accumulating experimental and clinical studies provide clear evidence for reversibility of hepatic fibrosis (HF).A......
Effects of vitamin E on the proliferation and collagen synthesis of rat hepatic stellate cells treat
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Differentially expressed genes identified by microarray analysis following leptin treatment of hepat
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Hepatitis B virus infects hepatic stellate cells and affects their proliferation and expression of c
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β-Arrestin2 deficiency attenuates oxidative stress in mouse hepatic fibrosis through modulation of N
Hepatic fibrosis is a disease characterized by excessive deposition of extracellular matrix(ECM)in the liver.Activation ......
Essential Roles of RNA-binding Protein HuR in Activation of Hepatic Stellate Cells Induced by Transf
Sphingosine kinase 1 (SphK1) is involved in transforming growth factor-β1 (TGF-β1)-induced hepatic stellate cells ......
Inhibitive effect of total alkaloids from Phyllodium pulchellum on collagen content and correlated c
Phyllodium pulchellum has been used as a folk remedy for the treatment of chronic hepatitis in China, and its benefi......
Background: Upon liver injury, quiescent hepatic stellate cells(q HSCs), reside in the perisinusoidal space, phenotypica......
Hepatic stellate cells(HSCs) are a kind of adipocytes. In HSCs lipids mainly exist in the form of lipid droplets. They a......
肝硬化是多种原因引起的慢性肝损伤所致的病理变化，是肝细胞外基质（ECM）产生与降解不平衡导致的纤维组织的过度堆积。肝星状细胞（ HSC ......
肝纤维化是各种慢性肝炎发展为肝硬化必经的病理阶段，同时也是向肝癌发展的中间环节。肝星状细胞（ HSC）是肝纤维化发生、发展的关键细......
Liver fibrosis is a gradual process of increased secretion and decreased degradation of extracellular materials (ECM). M......
Panax notoginseng saponins ameliorates experimental hepatic fibrosis and hepatic stellate cell proli
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肝硬化是各种肝脏疾病的终末期阶段，也是肝病患者死亡的主要原因。目前认为，肝硬化的过程不可逆且缺乏有效的治疗手段。长链非编码RN......
Effects of c-myb antisense RNA on TGF-β1 and α1-I collagen expression in cultured hepatic stellate c
AIM: To investigate the effects of c-myb antisense RNA on cell proliferation and the expression of c-myb, TGF-β1 and α......
AIM: To investigate the effects of herbal compound 861(Cpd 861) on cell proliferation in human hepatic stellate cells (L......
Effects of platelet-derived growth factor and interleukin-10 on Fas/Fas-ligand and Bcl-2/Bax mRNA ex
AIM: To investigate the effects of platelet-derived growthfactor(PDGF) and interleukin-10 (IL-10) on Fas/Fas-ligandand B......
Effects of endothelin- 1 on hepatic stellate cell proliferation, collagen synthesis and secretion, i
AIM: To explore the effects of endothelin-1(ET-1) on hepatic stellate cells (HSCs) DNA uptake, DNA synthesis, collagen s......
Effect of interleukin-10 and platelet-derived growth factor on expressions of matrix metalloproteina
AIM: To examine the expressions of matrix metalloproteinases-2 (MMP-2) and tissue inhibitor of metalloproteinases-1 (TIM......
Effect of rat serum containing Biejiajian oral liquid on proliferation of rat hepatic stellate cells
AIM: Liver fibrosis is a common pathological process of chronic liver diseases. Activation of hepatic stellate cells (HS......
AIM: To elucidate the mechanism by which somatostatin and its analogue exert the influence on liver fibrosis, and to inv......
Association of differentially expressed genes with activation of mouse hepatic stellate cells by hig
AIM: To characterize the gene expression profiles associated with activation of mouse hepatic stellate cell (HSC) and pr......
AIM: To observe the effect of compound Biejiaruangan decoction (CBJRGC) (composite prescription of Carapax trionycis for......
AIM: To study the reversing effect of Ginkgo biloba extract (GbE) on established liver fibrosis in rats.METHODS: Followi......
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AIM: To study the effects of Kupffer cell-conditioned medium (KCCM) derived from lipopolysaccharide (LPS) treatment on p......
